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Clin Diab 2022;40:3712

Unlike primary hypogonadism (testicular failure) or secondary hypogonadism (pituitary dysfunction), obesity-related hypogonadism is potentially reversible with significant weight loss

Traditional metformin therapy improves insulin sensitivity, while newer dual incretin agonists, such as tirzepatide, may offer broader metabolic and ovarian protection

Some experts have postulated that GLP-1 receptors could be protective against cytokine-mediated apoptosis (cell death) and may also stimulate neurogenesis (cell life)

Just let it come to a mild temperature naturally

Palvi Gupta is an employee of DRG Abacus Part of Clarivate